DSpace Collection:http://thuvienso.vanlanguni.edu.vn/handle/Vanlang_TV/36722024-03-29T00:07:11Z2024-03-29T00:07:11ZComputing Characterizations of Drugs for Ion Channels and Receptors Using Markov ModelsAslak TveitoGlenn T. Lineshttp://thuvienso.vanlanguni.edu.vn/handle/Vanlang_TV/348592021-10-23T07:51:44Z2016-01-01T00:00:00ZTitle: Computing Characterizations of Drugs for Ion Channels and Receptors Using Markov Models
Authors: Aslak Tveito; Glenn T. Lines
Abstract: Flow of ions through voltage gated channels can be represented theoretically using stochastic differential equations where the gating mechanism is represented by a Markov model. The flow through a channel can be manipulated using various drugs, and the effect of a given drug can be reflected by changing the Markov model. These lecture notes provide an accessible introduction to the mathematical methods needed to deal with these models. They emphasize the use of numerical methods and provide sufficient details for the reader to implement the models and thereby study the effect of various drugs. Examples in the text include stochastic calcium release from internal storage systems in cells, as well as stochastic models of the transmembrane potential. Well known Markov models are studied and a systematic approach to including the effect of mutations is presented. Lastly, the book shows how to derive the optimal properties of a theoretical model of a drug for a given mutation defined in terms of a Markov model.
Description: xvi, 261 p. : ill ; https://doi.org/10.1007/978-3-319-30030-6 CC BY-NC2016-01-01T00:00:00ZMARE-WINT: New Materials and Reliability in Offshore Wind Turbine TechnologyWiesław OstachowiczMalcolm McGuganJens-Uwe Schröder-HinrichsMarcin Luczakhttp://thuvienso.vanlanguni.edu.vn/handle/Vanlang_TV/348492021-10-23T07:30:22Z2016-01-01T00:00:00ZTitle: MARE-WINT: New Materials and Reliability in Offshore Wind Turbine Technology
Authors: Wiesław Ostachowicz; Malcolm McGugan; Jens-Uwe Schröder-Hinrichs; Marcin Luczak
Abstract: This book provides a holistic, interdisciplinary overview of offshore wind energy, and is a must-read for advanced researchers. Topics, from the design and analysis of future turbines, to the decommissioning of wind farms, are covered. The scope of the work ranges from analytical, numerical and experimental advancements in structural and fluid mechanics, to novel developments in risk, safety & reliability engineering for offshore wind.
Description: xi, 432 p. : ill ; https://doi.org/10.1007/978-3-319-39095-6 CC BY-NC2016-01-01T00:00:00ZA History of Radionuclide Studies in the UK: 50th Anniversary of the British Nuclear Medicine SocietyRalph McCreadyGopinath GnanasegaranJamshed B. Bomanjihttp://thuvienso.vanlanguni.edu.vn/handle/Vanlang_TV/348482021-10-23T07:28:10Z2016-01-01T00:00:00ZTitle: A History of Radionuclide Studies in the UK: 50th Anniversary of the British Nuclear Medicine Society
Authors: Ralph McCready; Gopinath Gnanasegaran; Jamshed B. Bomanji
Abstract: The British Nuclear Medicine Society celebrates its 50th Anniversary with this booklet, which reflects the research of many of the pioneers in the use of radionuclides for the diagnosis and therapy of human disease. Since 1949 there have been remarkable advances in radionuclide techniques and imaging equipment: from the first devices “home-made” in the many physics departments throughout the UK, to the sophisticated multimodality imagers now in everyday use in Nuclear Medicine. The BNMS has been instrumental in promoting the use of radionuclide techniques in the investigation of pathology by supporting and providing education, research and guidelines on the optimum use of radiation to help patients. The future of Nuclear Medicine is bright, thanks to improved imaging resolution, new radiopharmaceuticals, and new diagnostic and therapeutic techniques and procedures.
Description: xviii, 152 p. : ill ; https://doi.org/10.1007/978-3-319-28624-2 CC BY-NC2016-01-01T00:00:00ZQuantization on Nilpotent Lie GroupsVeronique FischerMichael Ruzhanskyhttp://thuvienso.vanlanguni.edu.vn/handle/Vanlang_TV/348412021-10-23T07:02:46Z2016-01-01T00:00:00ZTitle: Quantization on Nilpotent Lie Groups
Authors: Veronique Fischer; Michael Ruzhansky
Abstract: This book presents a consistent development of the Kohn-Nirenberg type global quantization theory in the setting of graded nilpotent Lie groups in terms of their representations. It contains a detailed exposition of related background topics on homogeneous Lie groups, nilpotent Lie groups, and the analysis of Rockland operators on graded Lie groups together with their associated Sobolev spaces. For the specific example of the Heisenberg group the theory is illustrated in detail. In addition, the book features a brief account of the corresponding quantization theory in the setting of compact Lie groups.
Description: xiii, 557 p. : ill ; https://doi.org/10.1007/978-3-319-29558-9 CC BY2016-01-01T00:00:00Z